MORE PREDICTABLE POST-OP IS FUNDAMENTAL TO IMPROVING GLAUCOMA SURGERY1-4
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Unpredictable patient outcomes remain a barrier to reliable long-term vision preservation.1,3,5,6
More Surgeon Perspectives
“Achieving lower pressures early on with safer options for patients will be beneficial in the long run.”
Sustainable Low IOP
“It’s really important to have a surgical approach where we can get the pressure down and it’s sustained over a significant period of time.”
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MIGS is not yet able to reliably achieve the low IOP of trabeculectomy3,7-10
*Not a head-to-head comparison. Based on findings from the TVT Study and the COMPARE Study.7,10
The post-op period of trabeculectomy can often be unpredictable1,3,5,6
§Based on findings from Gedde 2018.
A micro-invasive device that achieves low IOP similar to trabeculectomy but with a more predictable post-op would help surgeons consider earlier surgical intervention.3,5-7,9,11
References: 1. Amoozgar B, Wei X, Lee JH, et al. A novel flexible microfluidic meshwork to reduce fibrosis in glaucoma surgery. PLoS One. 2017;12(3):e0172556. 2. Chan JE, Netland PA. EX-PRESS Glaucoma Filtration Device: efficacy, safety, and predictability. Med Devices (Auckl). 2015;8:381-388. 3. Bloom P, Au L. “Minimally invasive glaucoma surgery (MIGS) is a poor substitute for trabeculectomy”—the great debate. Ophthalmol Ther. 2018;7(2):203-210. 4. Manasses DT, Au L. The new era of glaucoma micro-stent surgery. Ophthalmol Ther. 2016;5(2):135-146. 5. Nilforushan N, Yadgari M, Astaraki A, Miraftabi A. Comparison of the long-term outcomes of resident versus attending performed trabeculectomy. J Curr Ophthalmol. 2017;29(3):169-174. 6. King AJ, Rotchford AP, Alwitry A, Moodie J. Frequency of bleb manipulations after trabeculectomy surgery. Br J Ophthalmol. 2007;91(7):873-877. 7. Ahmed IIK, Fea A, Au L, et al. A prospective randomized trial comparing Hydrus and iStent microinvasive glaucoma surgery implants for standalone treatment of open-angle glaucoma: the COMPARE Study. Ophthalmology. 2020;127(1):52-61. 8. Ayyala RS, Arosemena A, Jewelewicz D, et al. Xen Gel Stent early results: safety and efficacy in the short term. Paper presented at: American Glaucoma Society Annual Meeting; March 1-4, 2018; New York, NY. 9. Agrawal P, Bradshaw SE. Systematic literature review of clinical and economic outcomes of micro-invasive glaucoma surgery (MIGS) in primary open-angle glaucoma. Ophthalmol Ther. 2018;7(1):49-73. 10. Gedde SJ, Schiffman JC, Feuer WJ, et al; Tube Versus Trabeculectomy Study Group. Treatment outcomes in the Tube Versus Trabeculectomy (TVT) Study after five years of follow-up. Am J Ophthalmol. 2012;153(5):789-803.e2. 11. Gedde SJ, Feuer WJ, Shi W, et al; Primary Tube Versus Trabeculectomy Study Group. Treatment outcomes in the primary Tube Versus Trabeculectomy Study after 1 year of follow-up. Ophthalmology. 2018;125(5):650-663. 12. Gedde SJ, Schiffman JC, Feuer WJ, et al; Tube Versus Trabeculectomy Study Group. Three-year follow-up of the Tube Versus Trabeculectomy Study. Am J Ophthalmol. 2009;148(5):670-684.